The Guardian called TTIP “the most controversial trade deal ever negotiated by the EU.”  TTIP negotiations are criticised and rejected by some trade unions, charities, NGOs and environmentalists, particularly in Europe.   The Independent summarizes the negative effects of TTIP as “reducing regulatory barriers to large companies, food security, environmental legislation, banking regulation and sovereigns of different nations” or more critical than “the attack on European and American companies by transnational groups”.  German economist Max Otte stated that proposed arbitration (ISDR) and the protection of foreign investment would mean a “total deviation from policy” and that free trade agreements on the labour economy would generally apply lower standards and that the TTIP would put European workers in direct competition with the Americans (and, in fact, under the North American free trade agreement with the Mexicans). which would have an impact on European social models.  Otte also concluded: “We really don`t want the social system of these countries [U.S. and Mexico] here [in Europe].”  In February 2013, US President Barack Obama used his State of the Union address to announce the opening of negotiations for a comprehensive free trade and investment agreement between the United States and the European Union. The first round of negotiations, which took place in July of the same year, was the realization of a dream that the economic lobbyists of the transatlantic economic dialogue, which had insisted since the 1990s for a free trade agreement between the EU and the United States, had long been achieved. Nevertheless, the Transatlantic Trade and Investment Partnership (TTIP) is more ambitious than any previous trade agreement, covering a wide range of topics, in order to reorganize the social and economic landscape on both sides of the Atlantic for the benefit of capital. Liberalisation of cross-border trade in services; and in 2016, Greenpeace published 248 pages of classified information from the TTIP trade negotiations.  Greenpeace Netherlands said it had published the documents “to ensure the necessary transparency and to stimulate an informed debate on the treaty.”  U.S. investment in the European Union is three times higher than U.S. investment across the Asian continent, and EU investment in the United States is eight times higher than EU investment in India and China combined.
It is estimated that intra-company transfers account for one third of total transatlantic trade. The United States and the European Union are the main trading partners of most other countries in the world and account for one-third of global trade flows.